Xarelto is also known as rivaroxaban. A factor Xa inhibitor, it prevents deep vein thrombosis and can result in pulmonary embolism particularly in patients undergoing hip replacement or knee surgery. Some of the most common side effects of Xarelto are bleeding complications, itching, leg and arm pain, fainting, muscle spasms and muscle pain. The Xarelto can be taken orally in quantities of 10mg before or after food. There are chances the Xarelto with other antifungal, anticoagulant, antibiotics and non-steroidal medicines. The drug reacts with salicylates, conivaptan, bosentan, aspirin, rifamycins, verapamil, barbiturates, dexamethasone and other blood and heart medications. There are reports it interacts with HIV medicines, seizure medications, abciximab, urokin and others.
Inform your doctor if you are on the medication and before taking any other medicines. Xarelto is not safe in pregnant and nursing women. In fact, it could harm the infant. Breastfeeding women have to be cautious with this medicine. The list of side effects occurring on taking Xarelto is not complete. If you suspect any discomfort report to the doctor immediately. Take medical advice or call the FDA to report the side effects. http://sideeffectsofxarelto.org/ is a website on Xarelto side effects. Find the list of Xarelto side effects at http://www.webmd.com/drugs/2/drug-156265/xarelto-oral/details/list-sideeffects.
On the first signs of allergy get emergency help. Allergies can be related to difficulty in breathing, swelling of the face, tongue, lips and throat, hives. Other side effects include bruising, bleeding in the noise, mouth, vagina or rectum. If the bleed is intense from the wounds report immediately. The medicine has to be stopped if you have heavy menstrual bleeding. Discontinue the medicine if you have dizziness, headaches, fatigue, red urine or a feeling you might pass out. Also, do not take the medicine if you have bloody or dark colored stools. Sometime there may be symptoms of vomiting or coughing up blood, it is time to say no to the medicine. Other safe side effects include itching or muscle pain.
Adverse reactions could lead to risk of a stroke, bleeding and spinal hematoma. The clinical trials happen under varied conditions and the adverse reactions are observed under clinical trial. The rates cannot be compared to the effect of the drug outside clinical practice. The most common adverse reactions happen long after the drug is discontinued and these are described by bleeding events.
The adverse reactions by post approval use of rivaroxaban reported by a voluntary population reveals the blood and lymphatic system disorder, hepatobillary disorder, gastrointestinal disorder, immune system disorder, subcutaneous and skin disorder, nervous system disorder and more.
Among the adverse reactions is Hemorrhage The reactions as a result of drug discontinuation for ever includes events of bleeding. The rate of incidence is 4.3% when compared to warfarin which is 3.1%. The non bleeding events are similar among both drug groups.
The studies explain the treatment of pulmonary embolism, deep vein thrombosis and reducing the risk of DVT and PE recurrence. The analysis of Einstein DVT and Einstein PE studies on permanent discontinuation of the drug, leads to bleeding events with the incidence rate of 1.7% for Xarelto and 1.5% for Enoxaparin.